Single Cell Clone Screening Platform

Single cell clone screening, also called monoclone screening is an important technology to separate individual cells from mixed cell samples according to the characteristics they possess in order to obtain highly homogeneous cells. The single cell clone screening platform provided by EDITGENE adopts the industry's top 3D single-cell printing technology, which is capable of isolating and localizing individual cells with high precision.

3D single-cell printing technology adopts non-contact operation, avoiding mechanical damage and background contamination; helping to maintain cell integrity and biological activity. 3D single-cell printing technology can avoid human errors from traditional limited dilution method and ensure the reliability of the screening results. Thus, researchers would be able to accurately isolate and localize individual cells, which can greatly improve the success rate and work efficiency of single cell clone screening.


This technology is widely used in biopharmaceutical research and development, antibody development, drug screening, therapeutic selection, and has a wide range of applications in the field of cell research.



Workflow


Case study
Single-cell clone isolation for S100A6 overexpression stable SV-HUC-1 cell line

Western blot result

Figure 1. #1-6 are clones of S100A6 overexpression stable SV-HUC-1 cells

S100A6 overexpression stable SV-HUC-1 cell clones have bands with desired size, meaning that the overexpression clones are useful for continuous study.