CRISPR detection is a technology that utilizes the CRISPR-Cas system for nucleic acid detection. In the field of molecular diagnostics, CRISPR technology has been developed into a highly sensitive, highly specific, and cost-effective diagnostic platform due to its ability to recognize and cut specific DNA or RNA sequences, providing a new method for pathogen nucleic acid detection. The advantages of CRISPR detection technology include its rapid, sensitive, and highly specific nature, along with relatively low costs, making it suitable for rapid on-site testing. Currently, the most commonly used methods are based on the intrinsic properties of Cas12 and Cas13 proteins, combined with signal amplification techniques (such as fluorescence) for molecular detection.
EDITGENE has developed a high-sensitivity, high-specificity, rapid isothermal nucleic acid detection technology based on CRISPR detection—FASST Rapid Detection Technology. This technology addresses issues in traditional CRISPR detection, such as complex operations, contamination risk, low sensitivity, and long processing times. By optimizing Cas enzyme structure through a proprietary protein purification platform, developing unique crRNA design logic, producing high-efficiency crRNA, and using a custom-designed reporter, EDITGENE enhances detection sensitivity, simplifies operational steps, and reduces contamination risk.