EGR1 Knockout THP-1 Cell Line
EGR1 Knockout THP-1 Cell Line is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performance Cas9 Protein and Hassle-Free Cell Selection.
Product Details
| Cat.No. | EDC10121 | Product Name | EGR1 Knockout THP-1 Cell Line |
|---|---|---|---|
| Cell Line | THP-1 | Cellosaurus ID | CVCL_0006 |
| Cell Line Synonyms | THP1, THP 1, THPI, THP-1(ATCC), THP-1-O, O-THP-1, Tohoku Hospital Pediatrics-1 | Passage Ratio | 1：2，2-3 days |
| Gene | Gene Synonyms | AT225|G0S30|KROX-24|NGFI-A|TIS8|ZIF-268|ZIF268|ZNF225 | |
| NCBI Gene ID | Summary |
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
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| Associated Diseases | Acute Myeloid Leukemia | Complete Culture Medium | RPMI-1640 + 10% FBS |
| Freezing Medium | Complete medium + 30% FBS + 5% DMSO | QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
STR Profile
| Loci | STR Info (Sample Cell) Sample Cell Line: THP-1 | STR Info (Cell bank) Cell Line: THP-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 11 | 13 | 11 | 13 |
| D1S1656 | 16 | 17 | 16 | 17 |
| D2S1338 | 17 | 18 | 17 | 18 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 10 | 14 | 10 | 14 |
| D12S391 | 19 | 18 | 19 | |
| D13S317 | 13 | 13 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 12.2 | 13 | 12.2 | 13 |
| D21S11 | 30 | 31.2 | 30 | 31.2 |
| FGA | 24 | 25 | 24 | 25 |
| Penta D | 10 | 12 | 10 | 12 |
| Penta E | 11 | 15 | 11 | 15 |
| TH01 | 8 | 9.3 | 8 | 9.3 |
| TPOX | 8 | 11 | 8 | 11 |
| VWA | 16 | 16 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
