EGR1 Knockout THP-1 Cell Line
Cat.No.:
EDC10121
Species:
Human
Cell Name:
THP-1
Gene:
EGR1
Gene ID:
1958
Size:
1×10⁶cells
EGR1 Knockout THP-1 Cell Line is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performance Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDC10121 |
|---|---|
| Product Name | EGR1 Knockout THP-1 Cell Line |
| Cell Line | THP-1 |
| Cellosaurus ID | CVCL_0006 |
| Cell Line Synonyms | THP1, THP 1, THPI, THP-1(ATCC), THP-1-O, O-THP-1, Tohoku Hospital Pediatrics-1 |
| Passage Ratio | 1：2，2-3 days |
| Gene |
EGR1
|
| Gene Synonyms | AT225|G0S30|KROX-24|NGFI-A|TIS8|ZIF-268|ZIF268|ZNF225 |
| NCBI Gene ID | |
| Summary |
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
|
| Associated Diseases | Acute Myeloid Leukemia |
| Complete Culture Medium | RPMI-1640 + 10% FBS |
| Freezing Medium | Complete medium + 30% FBS + 5% DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: THP-1 | STR Info (Cell bank) Cell Line: THP-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 11 | 13 | 11 | 13 |
| D1S1656 | 16 | 17 | 16 | 17 |
| D2S1338 | 17 | 18 | 17 | 18 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 10 | 14 | 10 | 14 |
| D12S391 | 19 | 18 | 19 | |
| D13S317 | 13 | 13 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 12.2 | 13 | 12.2 | 13 |
| D21S11 | 30 | 31.2 | 30 | 31.2 |
| FGA | 24 | 25 | 24 | 25 |
| Penta D | 10 | 12 | 10 | 12 |
| Penta E | 11 | 15 | 11 | 15 |
| TH01 | 8 | 9.3 | 8 | 9.3 |
| TPOX | 8 | 11 | 8 | 11 |
| VWA | 16 | 16 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Verified Publications
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis
IF=3.3
Wiley
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