EGR1 Knockout THP-1 Cell Line
Cat.No.:
EDJ-KZ21
Species:
Human
Cell Name:
THP-1
Gene:
EGR1
Gene ID:
1958
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ21 |
|---|---|
| Product Name | EGR1 Knockout THP-1 Cell Line |
| Cell Line | THP-1 |
| Cellosaurus ID | CVCL_0006 |
| Cell Line Synonyms | THP1, THP 1, THPI, THP-1(ATCC), THP-1-O, O-THP-1, Tohoku Hospital Pediatrics-1 |
| Gene | EGR1 |
| Gene Synonyms | AT225|G0S30|KROX-24|NGFI-A|TIS8|ZIF-268|ZIF268|ZNF225 |
| Summary |
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
|
| Associated Diseases | Acute Myeloid Leukemia |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: THP-1 | STR Info (Cell bank) Cell Line: THP-1 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 11 | 13 | 11 | 13 |
| D1S1656 | 16 | 17 | 16 | 17 |
| D2S1338 | 17 | 18 | 17 | 18 |
| D3S1358 | 15 | 17 | 15 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 10 | 14 | 10 | 14 |
| D12S391 | 19 | 18 | 19 | |
| D13S317 | 13 | 13 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 12.2 | 13 | 12.2 | 13 |
| D21S11 | 30 | 31.2 | 30 | 31.2 |
| FGA | 24 | 25 | 24 | 25 |
| Penta D | 10 | 12 | 10 | 12 |
| Penta E | 11 | 15 | 11 | 15 |
| TH01 | 8 | 9.3 | 8 | 9.3 |
| TPOX | 8 | 11 | 8 | 11 |
| VWA | 16 | 16 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Verified Publications
Conditioned Medium Derived From Human Dental Follicle Mesenchymal Stem Cells Alleviates Macrophage Proinflammatory Responses Through MAPK-ERK-EGR1 Axis
IF=3.3
Wiley
Required Accessories
Cell Culture Optimization Series
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