Chemical Synthesis of siRNA

EDITGENE provides both ready-to-use and rapid custom chemical synthesis of siRNA for human, rat, and mouse, meeting immediate and personalized needs of researchers. To ensure more efficient gene screening, we also offer FAM-labeled control siRNA, which allows clear monitoring of transfection efficiency and ensures reliable experimental results.  更多

货号 : EDN-RI01

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Applications

1.Gene Function Studies: By designing siRNA targeting specific genes, researchers can rapidly and reversibly reduce the expression of those genes and observe resulting phenotypic changes in cells or organisms (such as alterations in proliferation, differentiation, apoptosis, migration, or metabolism), thereby inferring the function of the target gene.
2.Signal Pathway Analysis: siRNA can be used to study the roles of individual components within complex signaling pathways. By sequentially silencing different genes in a pathway, researchers can reveal upstream-downstream relationships and interactions among pathway components.
3.Drug Target Screening and Validation: In early drug development, siRNA can silence potential drug target genes to mimic the effects of pharmacological inhibition. This approach allows assessment of therapeutic potential and possible side effects, facilitating the screening and validation of valuable targets.

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